PTEN/Akt Axis is Involved in Somatic Cell Reprogramming to Mouse iPS Cells

Abstract
Induced pluripotent stem cells (iPSCs) are highly expected to apply for regeneration therapy and disease modeling, although the efficiency of reprogramming to iPSCs remains not high enough. We previously reported that inhibition of p53 tumor suppressor gene exhibits a remarkable increase in the efficiency of reprogramming to iPSCs.

This publication has 0 references indexed in Scilit: