PTEN/Akt Axis is Involved in Somatic Cell Reprogramming to Mouse iPS Cells
Open Access
- 10 December 2018
- journal article
- Published by Biomedical Research Network, LLC in Biomedical Journal of Scientific & Technical Research
- Vol. 11 (5) , 001-007
- https://doi.org/10.26717/bjstr.2018.11.002162
Abstract
Induced pluripotent stem cells (iPSCs) are highly expected to apply for regeneration therapy and disease modeling, although the efficiency of reprogramming to iPSCs remains not high enough. We previously reported that inhibition of p53 tumor suppressor gene exhibits a remarkable increase in the efficiency of reprogramming to iPSCs.Keywords
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