Jiawei Zhou
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Jiawei Zhou has a total of 20 co-authors. Here are the top co-authors by number of shared publications:
- Chan Min
Institute of Fermentation Engineering, Zhejiang University of Technology, Hangzhou, People’s Republic of China
1 shared publication Dengyu Li
School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China
1 shared publication- Dong Zhang
College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310014, China
1 shared publication Gaowei Fang
School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China
1 shared publication- Hanchi Chen
Zhejiang University of Technology
1 shared publication Jing Ma
School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China
1 shared publication
Latest Publications
- 11 June 2025
- Published by Elsevier in International Journal of Biological Macromolecules
- Vol. 318 (Pt 3) , 145152
Multifunctional sesquiterpene synthase from Curcuma wenyujin reveals the biosynthetic mechanism of sesquiterpenes with diverse skeletons
- 11 June 2025
- Published by Elsevier in International Journal of Biological Macromolecules
- Vol. 318 (Pt 3) , 145152
Multifunctional sesquiterpene synthase from Curcuma wenyujin reveals the biosynthetic mechanism of sesquiterpenes with diverse skeletons
- 2 December 2021
- Published by Springer Nature in 3 Biotech
- Vol. 12 (1) , 1-12
Efficient production of valinomycin by the soil bacterium, Streptomyces sp. ZJUT-IFE-354
A novel strain with antifungal activity against Sclerotinia sclerotiorum was isolated from soil, and identified as Streptomyces sp. ZJUT-IFE-354 using morphological and 16S rDNA sequence analysis. The bioactive metabolite produced by strain ZJUT-IFE-354 was identified and characterized as valinomycin by spectroscopic and chemical methods. The yield of valinomycin was 191.26 mg/L from the culture of Streptomyces sp. ZJUT-IFE-354, which was the highest yield to our knowledge. The in vitro antifungal activity of valinomycin against S. sclerotiorum was investigated as 0.056 ± 0.012 (EC50) and 0.121 ± 0.023 μg/mL (EC95), respectively, which was approximately 10.696- and 30.960-fold more active than that of carbendazim. The results from scanning electron microscopy, cell membrane permeability, and D-sorbitol and ergosterol assay indicated that valinomycin exerted the antifungal activity probably by increasing permeability of fungal cell membrane, leading to mycelial electrolyte leakage, and eventually resulting in the death of S. sclerotiorum. Thus, valinomycin may be a promising antifungal agent to control S. sclerotiorum.
- 2 December 2021
- Published by Springer Nature in 3 Biotech
- Vol. 12 (1) , 1-12
Efficient production of valinomycin by the soil bacterium, Streptomyces sp. ZJUT-IFE-354
A novel strain with antifungal activity against Sclerotinia sclerotiorum was isolated from soil, and identified as Streptomyces sp. ZJUT-IFE-354 using morphological and 16S rDNA sequence analysis. The bioactive metabolite produced by strain ZJUT-IFE-354 was identified and characterized as valinomycin by spectroscopic and chemical methods. The yield of valinomycin was 191.26 mg/L from the culture of Streptomyces sp. ZJUT-IFE-354, which was the highest yield to our knowledge. The in vitro antifungal activity of valinomycin against S. sclerotiorum was investigated as 0.056 ± 0.012 (EC50) and 0.121 ± 0.023 μg/mL (EC95), respectively, which was approximately 10.696- and 30.960-fold more active than that of carbendazim. The results from scanning electron microscopy, cell membrane permeability, and D-sorbitol and ergosterol assay indicated that valinomycin exerted the antifungal activity probably by increasing permeability of fungal cell membrane, leading to mycelial electrolyte leakage, and eventually resulting in the death of S. sclerotiorum. Thus, valinomycin may be a promising antifungal agent to control S. sclerotiorum.