Changhui Zhao
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Changhui Zhao has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Chong Lei
National Key Laboratory of Advanced Micro and Nano Manufacture Technology, Department of Micro-Nano Electronics, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
1 shared publication - Chunming Ren
School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China
1 shared publication - Hao Sun
Microelectronics Research & Development Center, School of Mechatronics Engineering and Automation, Shanghai University, Shanghai 200444, China
1 shared publication - Jiao Li
Microelectronics Research Development Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China
1 shared publication - Shenghao Li
Microelectronics Research & Development Center, School of Mechatronics Engineering and Automation, Shanghai University, Shanghai 200444, China
1 shared publication - Xuecheng Sun
Research and Development Center of Microelectronics, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China
1 shared publication
Latest Publications
- Open Access
Geometric Optimization of GMR Biosensors with Trapezoidal Magnetic Flux Concentrators for Detecting Bacillus anthracis in Complex Matrices
Background noise and intensive sample preparation frequently compromise the field screening of Bacillus anthracis. Addressing these analytical bottlenecks, we constructed a giant magnetoresistive (GMR) biosensor incorporating geometrically tailored trapezoidal magnetic flux concentrators (MFCs). 3D finite element magnetic simulations directed the MFC topology to mitigate edge saturation, reconciling central magnetic gain with spatial uniformity. The resulting platform demonstrated a 100-fold sensitivity improvement over recent electrochemical methods, achieving a limit of detection (LOD) of 10 CFU/mL in standard buffers, with the entire testing process completed within 40 min. Direct target quantification remained viable in heterogeneous matrices—muddy water, whole milk, and apple cider—circumventing tedious pretreatment. This geometric and magnetic optimization yields a pragmatic sensing architecture tailored for on-site biodefense monitoring.
Open AccessGeometric Optimization of GMR Biosensors with Trapezoidal Magnetic Flux Concentrators for Detecting Bacillus anthracis in Complex Matrices
Background noise and intensive sample preparation frequently compromise the field screening of Bacillus anthracis. Addressing these analytical bottlenecks, we constructed a giant magnetoresistive (GMR) biosensor incorporating geometrically tailored trapezoidal magnetic flux concentrators (MFCs). 3D finite element magnetic simulations directed the MFC topology to mitigate edge saturation, reconciling central magnetic gain with spatial uniformity. The resulting platform demonstrated a 100-fold sensitivity improvement over recent electrochemical methods, achieving a limit of detection (LOD) of 10 CFU/mL in standard buffers, with the entire testing process completed within 40 min. Direct target quantification remained viable in heterogeneous matrices—muddy water, whole milk, and apple cider—circumventing tedious pretreatment. This geometric and magnetic optimization yields a pragmatic sensing architecture tailored for on-site biodefense monitoring.