Epidermal Growth Factor Receptor and K-RAS status in two cohorts of squamous cell carcinomas
Authors:
- Nancy Van DammeNDNancy Van Damme
- Philippe DeronPDPhilippe Deron
- Nadine Van RoyNRNadine Van Roy
- Pieter DemetterPDPieter Demetter
- Alain BolsABAlain Bols
- Jo Van DorpeJDJo Van Dorpe
- Filip BaertFBFilip Baert
- Jean-Luc Van LaethemJLJean-Luc Van Laethem
- Franki SpelemanFSFranki Speleman
- Patrick PauwelsPPPatrick Pauwels
- Marc PeetersMPMarc Peeters
Open Access
- 11 May 2010
- journal article
- research article
- Published by Springer Nature in BMC Cancer
- Vol. 10 (1) , 189
Abstract
With the availability of effective anti-EGFR therapies for various solid malignancies, such as non-cell small lung cancer, colorectal cancer and squamous cell carcinoma of the head and neck, the knowledge of EGFR and K-RAS status becomes clinically important. The aim of this study was to analyse EGFR expression, EGFR gene copy number and EGFR and K-RAS mutations in two cohorts of squamous cell carcinomas, specifically anal canal and tonsil carcinomas.Keywords
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