Empty virions in AAV8 vector preparations reduce transduction efficiency and may cause total viral particle dose-limiting side effects
Open Access
- 1 January 2014
- journal article
- Published by Elsevier in Molecular Therapy - Methods & Clinical Development
- Vol. 1 (9) , 9
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- CpG-depleted adeno-associated virus vectors evade immune detectionJournal of Clinical Investigation, 2013
- Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid TraffickingJournal of Virology, 2013
- Adeno-associated virus capsid antigen presentation is dependent on endosomal escapeJournal of Clinical Investigation, 2013
- Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia BNew England Journal of Medicine, 2011
- Preclinical Differences of Intravascular AAV9 Delivery to Neurons and Glia: A Comparative Study of Adult Mice and Nonhuman PrimatesMolecular Therapy, 2011
- Good Manufacturing Practice Production of Self-Complementary Serotype 8 Adeno-Associated Viral Vector for a Hemophilia B Clinical TrialHuman Gene Therapy, 2011
- Assessing the potential for AAV vector genotoxicity in a murine modelBlood, 2011
- BALB/c Mice Show Impaired Hepatic Tolerogenic Response Following AAV Gene Transfer to the LiverMolecular Therapy, 2010
- Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver†Hepatology, 2009
- Analytical Ultracentrifugation: Sedimentation Velocity and Sedimentation Equilibrium2008