Translation in vitro of vesicular stomatitis virus mRNA lacking 5′-terminal 7-methylguanosine

Authors:
  • JRJohn K. Rose
    John K. Rose
  • HLHarvey F. Lodish
    Harvey F. Lodish

Abstract
The 5'-terminus 7-methylguanosine of vesicular stomatitis virus mRNA is not essential for translation of the mRNA. The 7-methylguanosine seems to have a mediating rather than an obligatory role in ribosome binding by the mRNA and in mRNA translation.