Targeted degradation of Influenza a virus nucleoprotein via aptamer-based PROTACs for antiviral therapy

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Abstract
Influenza A virus (IAV) is the primary pathogen responsible for seasonal and pandemic influenza, causing 3 to 5 million severe cases and approximately 290,000 to 650,000 deaths annually worldwide [...
Funding Information
  • Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Project (2026ZD01999610)
  • Major Project of Guangzhou National Laboratory (GZNL2024A01016)
  • Major Project of Guangzhou National Laboratory (GZNL2025C01015)
  • Guangdong Special Support Plan on Young Topnotch Talents (2024TQ08A676)

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