Detection of group a human rotavirus G9 genotype circulating in Córdoba, Argentina, as early as 1980

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Abstract
The incidence of human rotavirus G types was determined over a 25‐year period (1979–2003) by using reverse transcription‐PCR (RT‐PCR) to examine 519 stool specimens found to be positive for rotavirus by enzyme linked immunosorbent assay (ELISA) or polyacrylamide gel electrophoresis (PAGE). These stool samples were obtained from children under 3 years old who had been treated for acute diarrhea at public hospitals in Córdoba, Argentina. The present study describes the continued circulation of the common human G types G1 (53.8%), G2 (10.2%), G3 (4.4%), and G4 (27%), and also the detection of the unusual types G8 (0.5%) and G9 (4.2%). Genotype G9 was detected during the 1980–1988 and 1997–2003 periods at relatively low rates. Rotavirus G types distribution was independent of age (1–18 months), gender or out‐patient or in‐patient status. Unexpectedly, 44.6% of mixed infections were detected, involving common and unusual genotypes. Overall, 95.4% of the typed strains belonged to the most prevalent human serotypes (G1–G4) but the detection of G9 infection throughout this study period highlights the importance of this serotype as a human pathogen. J. Med. Virol. 78:1113–1118, 2006.

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