Loss of BECN1 does not compromise autophagosome formation but alters cargo selection and HLA-restricted antigen presentation of B cells
Authors:
Open Access
- 26 August 2026
- journal article
- research article
- Published by Taylor & Francis in Autophagy
- p. 1-20
Abstract
Macroautophagy, hereafter referred to as autophagy, is a conserved, catabolic process that promotes cell survival by recycling unused or damaged cellular components and is enhanced in response to n...Keywords
Funding Information
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (310030_204470/1, 310030L_197952/1 and CRSII_222718_10000065)
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (316030_229588 and 310030_212187)
- Cancer Research Switzerland (KFS-5896–08-2023-R)
- Swiss State Secretariat for Education, Research and Innovation (101137235)
- Sobek Foundation, the Swiss Vaccine Research Institute
- Deutsche Forschungsgemeinschaft (EXC2180-390900677)
- Deutsche Forschungsgemeinschaft (WA 5340/6–1)
- Deutsche Krebshilfe (70114948)
- investBW (BW1_4064/03)
- Else Kröner Fresenius Foundation (EKFS 2022_EKSE.79)
- Carl-Zeiss-Stiftung (P2024-02–012)
- European Union’s research and innovation programme under the Marie Skłodowska-Curie (101119795)
This publication has 61 references indexed in Scilit:
- IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasionCell, 2024
- The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localizationCell Reports, 2024
- Expanding the Perseus Software for Omics Data Analysis With Custom PluginsCurrent Protocols in Bioinformatics, 2020
- Purification and Identification of Naturally Presented MHC Class I and II Ligands2019
- Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8+ T Cell ResponsesCell Reports, 2016
- Macroautophagy Proteins Assist Epstein Barr Virus Production and Get Incorporated Into the Virus ParticlesEBioMedicine, 2014
- EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor ChemoresistanceCell, 2013
- Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20Cellular and Molecular Life Sciences, 2011
- Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent AutophagyCell, 2005
- A simple method to eliminate the antigenicity of surface class I MHC molecules from the membrane of viable cells by acid treatment at pH 3Journal of Immunological Methods, 1987