Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
Authors:
Open Access
- 1 June 2019
- journal article
- research article
- Published by Elsevier in Cell Reports
- Vol. 27 (10) , 2948-2961.e7
Abstract
No abstract availableKeywords
Funding Information
- Deutsche Forschungsgemeinschaft
- National Research Foundation of Korea
- Ministry of Science ICT and Future Planning
This publication has 50 references indexed in Scilit:
- Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunityNature Immunology, 2013
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cellsJournal of Experimental Medicine, 2011
- Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cellsNature, 2010
- The Lkb1 metabolic sensor maintains haematopoietic stem cell survivalNature, 2010
- Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cellsNature, 2010
- Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscleProceedings of the National Academy of Sciences, 2010
- The LKB1–AMPK pathway: metabolism and growth control in tumour suppressionNature Reviews Cancer, 2009
- Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivoNature Immunology, 2009
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage CommitmentImmunity, 2009
- Regulation of the mevalonate pathwayNature, 1990