Cucurbit[8]uril-based supramolecular polymer nanocapsules as an effective siRNA delivery platform for gene therapy
- 2 October 2019
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Polymer Chemistry
- Vol. 10 (41) , 5659-5664
Abstract
An effective siRNA delivery platform was constructed by supramolecular self-assembly to achieve enhanced transfection efficiency and the gene silencing effect.Keywords
Funding Information
- National Natural Science Foundation of China (21420102007)
- National Natural Science Foundation of China (21574056)
- National Key Research and Development Program of China (2018YFA0901600)
This publication has 44 references indexed in Scilit:
- Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticlesNature, 2010
- The promises and pitfalls of RNA-interference-based therapeuticsNature, 2009
- Cucurbit[n]urils: from mechanism to structure and functionChemical Communications, 2008
- Interfering with disease: a progress report on siRNA-based therapeuticsNature Reviews Drug Discovery, 2007
- pH-Responsive Aggregates from Double Hydrophilic Block Copolymers Carrying Zwitterionic Groups. Encapsulation of Antiparasitic Compounds for the Treatment of LeishmaniasisLangmuir, 2007
- The Cucurbit[n]uril FamilyAngewandte Chemie International Edition, 2005
- A supramolecular poly[3]pseudorotaxane by self-assembly of a homoditopic cylindrical bis(crown ether) host and a bisparaquat derivativeChemical Communications, 2005
- Enzymatic Formation of Supramolecular HydrogelsAdvanced Materials, 2004
- Polymeric Rotaxane Constructed from the Inclusion Complex of β‐Cyclodextrin and 4,4′‐Dipyridine by Coordination with Nickel(II) IonsAngewandte Chemie International Edition, 2003
- Supramolecular Pseudorotaxane Polymers from Complementary Pairs of Homoditopic MoleculesJournal of the American Chemical Society, 2003