Archiving mouse strains by cryopreservation
- 1 April 2005
- journal article
- review article
- Published by Springer Nature in Lab Animal
- Vol. 34 (4) , 50-57
Abstract
A great deal of time and energy goes into the creation of each new line of transgenic mice; established lines are expensive and labor-intensive to maintain. Archiving of mice by cryopreservation of germ cells or embryos represents a means to free up facility space, while protecting the line from loss due to environmental disasters, genetic drift, or infectious disease. The author reviews the available cryopreservation techniques and presents considerations for setting up a cryopreservation facility.Keywords
This publication has 42 references indexed in Scilit:
- Production of transgenic mice from vitrified pronuclear‐stage embryosMolecular Reproduction and Development, 2002
- Research Toll Is Heavy in Time and MoneyScience, 2001
- Positive Effect of Partial Zona-Pellucida Dissection on the in Vitro Fertilizing Capacity of Cryopreserved C57BL/6J Transgenic Mouse Spermatozoa of Low MotilityBiology of Reproduction, 1997
- Simple and Efficient Vitrification Procedure for Cryopreservation of Mouse Embryos.Experimental Animals, 1997
- Rederivation of Mice by Means of In Vitro Fertilization and Embryo Transfer.Experimental Animals, 1996
- Oocyte and zygote zona pellucida permeability to macromoleculesJournal of Experimental Zoology, 1995
- Studies on Cryopreservation of Embryos and Gametes in Mice.Experimental Animals, 1995
- Fire devastates Jackson labScience, 1989
- Mouse embryo cryobankingJournal of Assisted Reproduction and Genetics, 1986
- Ice-free cryopreservation of mouse embryos at −196 °C by vitrificationNature, 1985