In vivo evidence that retinal bipolar cells generate spikes modulated by light
Open Access
- 26 June 2011
- journal article
- research article
- Published by Springer Nature in Nature Neuroscience
- Vol. 14 (8) , 951-952
Abstract
It is thought that retinal bipolar cells do not fire action potentials, but calcium imaging in live zebrafish now reveals that in bipolar cells there are 'all or none' calcium transients that are modulated by visual stimulation. Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation.Keywords
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