Genomicus: five genome browsers for comparative genomics in eukaryota
Open Access
- 26 November 2012
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 41 (D1) , D700-D705
Abstract
Genomicus (http://www.dyogen.ens.fr/genomicus/) is a database and an online tool that allows easy comparative genomic visualization in >150 eukaryote genomes. It provides a way to explore spatial information related to gene organization within and between genomes and temporal relationships related to gene and genome evolution. For the specific vertebrate phylum, it also provides access to ancestral gene order reconstructions and conserved non-coding elements information. We extended the Genomicus database originally dedicated to vertebrate to four new clades, including plants, non-vertebrate metazoa, protists and fungi. This visualization tool allows evolutionary phylogenomics analysis and exploration. Here, we describe the graphical modules of Genomicus and show how it is capable of revealing differential gene loss and gain, segmental or genome duplications and study the evolution of a locus through homology relationships.Keywords
This publication has 14 references indexed in Scilit:
- Ensembl 2012Nucleic Acids Research, 2011
- Ensembl Genomes: an integrative resource for genome-scale data from non-vertebrate speciesNucleic Acids Research, 2011
- GSV: a web-based genome synteny viewer for customized dataBMC Bioinformatics, 2011
- SyMAP v3.4: a turnkey synteny system with application to plant genomesNucleic Acids Research, 2011
- eGOB: eukaryotic Gene Order BrowserBioinformatics, 2011
- The UCSC Genome Browser database: update 2011Nucleic Acids Research, 2010
- EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebratesGenome Research, 2008
- SynView: a GBrowse-compatible approach to visualizing comparative genome dataBioinformatics, 2006
- The tree of eukaryotesTrends in Ecology & Evolution, 2005
- SynBrowse: a synteny browser for comparative sequence analysisBioinformatics, 2005