Prodrugs of Phosphonates, Phosphinates, and Phosphates

This publication has 60 references indexed in Scilit:

• Design and development of oral drugs for the prophylaxis and treatment of smallpox infection
  Trends in Biotechnology, 2004
• Design, Synthesis, and Characterization of a Series of Cytochrome P₄₅₀3A-Activated Prodrugs (HepDirect Prodrugs) Useful for Targeting Phosph(on)ate-Based Drugs to the Liver^§
  Journal of the American Chemical Society, 2004
• The cyclic congener of cidofovir has reduced nephrotoxicity in three species
  Antiviral Research, 1995
• Intracellular delivery of nucleoside monophosphates through a reductase-mediated activation process
  Antiviral Research, 1993
• Nucleoside analogues previously found to be inactive against HIV may be activated by simple chemical phosphorylation
  FEBS Letters, 1993
• Synthesis, bioactivation and anti-HIV activity of the bis(4-acyloxybenzyl) and mono(4-acyloxybenzyl) esters of the 5′-monophosphate of AZT
  Journal of the Chemical Society, Perkin Transactions 1, 1993
• Phosphate derivatives of AZT display enhanced selectivity of action against HIV1 by comparison to the parent nucleoside
  FEBS Letters, 1992
• Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine
  Antiviral Research, 1992
• Lipophilic 5'-alkyl phosphate esters of 1-.beta.-D-arabinofuranosylcytosine and its N4-acyl and 2,2'-anhydro-3'-O-acyl derivatives as potential prodrugs
  Journal of Medicinal Chemistry, 1982
• Enzymic hydrolysis of phosphonate esters. Reaction mechanism of intestinal 5'-nucleotide phosphodiesterase
  Biochemistry, 1977