18F‐FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma

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Abstract
Objectives: To evaluate and compare the diagnostic potential of 18F‐fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18FDG‐PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC).Methods: A total of 32 dedicated head and neck 18F‐FDG PET/MRI datasets were included in this analysis. MRI and 18F‐FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases.Results: Lesion‐based sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy were 96%, 84%, 90%, 93%, and 91% for 18F‐FDG PET/MRI and 77%, 94%, 95%, 73%, and 84% for MRI, resulting in a significantly higher diagnostic accuracy of 18F‐FDG PET/MRI compared to MRI (P < .005).Conclusion: 18F‐FDG PET/MRI is superior to MRI in detecting local recurrence and metastases in patients with ACC of the head and neck. Especially concerning its negative predictive value, 18F‐FDG PET/MRI outperforms MRI.

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