An abdominal wall neuroendocrine tumor of unknown primary origin: A case report and review of the literature
Authors:
Open Access
- 10 February 2022
- journal article
- review article
- Published by Wiley in Cancer Reports
- Vol. 5 (9) , e1610
Abstract
Background: Neuroendocrine tumors (NETs) are neoplasms that arise from cells of the endocrine and nervous system. NETs, often found in the gastrointestinal tract, can be found anywhere in the body, and have metastatic potential. NETs occasionally present with metastatic disease without an identifiable primary tumor.Case: A 79‐year‐old female patient presented with an abdominal wall mass. Percutaneous biopsy was consistent with a NET. Preoperative endoscopy and PillCam were unremarkable. PET Dotatate demonstrated uptake in the abdominal wall as well as vague uptake in the pelvis. Intraoperatively, we identified a suspicious nodule on the sigmoid colon, which was consistent with a drop metastasis on final pathology.Conclusion: In this case report we present a patient with a NET metastasis to the abdominal wall without a known primary site. This case highlights the limitations of endoscopy and imaging in the workup of metastatic NETs. Additionally, this is a novel case report of a metastatic NET to the abdominal wall without an identifiable primary site.Keywords
This publication has 29 references indexed in Scilit:
- Metastatic Neuroendocrine Carcinoma of Unknown Origin Arising in the Femoral Nerve SheathWorld Neurosurgery, 2017
- Localization of Unknown Primary Site with 68Ga-DOTATOC PET/CT in Patients with Metastatic Neuroendocrine TumorJournal of Nuclear Medicine, 2017
- Identification of primary tumors in patients presenting with metastatic gastroenteropancreatic neuroendocrine tumorsSurgery, 2017
- The added value of 68Ga-DOTA-TATE-PET to contrast-enhanced CT for primary site detection in CUP of neuroendocrine originEuropean Radiology, 2016
- Neuroendocrine tumors (NETs) of unknown primary: is early surgical exploration and aggressive debulking justifiable?2016
- Nuclear imaging of neuroendocrine tumors with unknown primary: why, when and how?European Journal of Nuclear Medicine and Molecular Imaging, 2015
- CUP Syndrome in Neuroendocrine Neoplasia: Analysis of Risk Factors and Impact of Surgical InterventionWorld Journal of Surgery, 2015
- Surgery for metastatic neuroendocrine tumors with occult primariesJournal of Surgical Research, 2013
- Skeletal Muscle Metastases in a Patient With Neuroendocrine TumorWorld Journal of Oncology, 2013
- Clinical Course of Neuroendocrine Tumors With Different Origins (the Pancreas, Gastrointestinal Tract, and Lung)American Journal of Clinical Oncology, 2012