Photo- or Electrochemical Cyclization of Dienes with Diselenides to Access Seleno-Benzo[b]azepines
- 23 May 2023
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 88 (11) , 7245-7255
Abstract
A cascade selenylation/cyclization of dienes with diselenides has been realized under visible-light irradiation or electrolysis conditions. Employing O2 or electricity as a "green" oxidant, this protocol provides a green and efficient method for an array of biologically important seleno-benzo[b]azepine derivatives in moderate to good yields. The direct sunlight irradiation and gram-scale reaction render the approach practical and attractive.Keywords
Funding Information
- Yantai University (KGIFYTU2214)
- Natural Science Foundation of Shandong Province (ZR2020QB003)
- Qingchuang Technology Support Program of University in Shandong Province (2021KJ066)
- University Student Innovation and Entrepreneurship Training Program (X202211066034)
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