Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains

This publication has 63 references indexed in Scilit:

• Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
  Nature Biotechnology, 2012
• The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
  Molecular Cell, 2011
• Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression
  Cell, 2011
• Unexpected roles for core promoter recognition factors in cell-type-specific transcription and gene regulation
  Nature Reviews Genetics, 2010
• Using deep sequencing to characterize the biophysical mechanism of a transcriptional regulatory sequence
  Proceedings of the National Academy of Sciences, 2010
• Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
  The EMBO Journal, 2009
• Multiple Intrinsically Disordered Sequences Alter DNA Binding by the Homeodomain of the Drosophila Hox Protein Ultrabithorax
  Journal of Biological Chemistry, 2008
• ABSINTH: A new continuum solvation model for simulations of polypeptides in aqueous solutions
  Journal of Computational Chemistry, 2008
• VMD: Visual molecular dynamics
  Journal of Molecular Graphics, 1996
• Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features
  Biopolymers, 1983