Olfactory adenylate cyclase of the rat Stimulation by odorants and inhibition by Ca2+
Authors:
- S G ShirleySSS G Shirley
- C J RobinsonCRC J Robinson
- K DickinsonKDK Dickinson
- R AujlaRAR Aujla
- G H DoddGDG H Dodd
- 1 December 1986
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 240 (2) , 605-607
Abstract
Membranes prepared from olfactory mucosa of the rat show a high level of adenylase cyclase activity. The activity increases up to 2-fold in the presence of physiologically relevant concentrations of odorants and is inhibited by Ca2+. The level of cyclase activity found is sufficient to explain the speed of olfactory transduction, which occurs on a time scale of tens of milliseconds.Keywords
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