Separation of Fe+3 from transferrin in endocytosis
Authors:
- K. RaoKRK. Rao
- J. van RenswoudeJRJ. van Renswoude
- C. KempfCKC. Kempf
- R.D. KlausnerRKR.D. Klausner
- 22 August 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 160 (1-2) , 213-216
Abstract
NH4Cl and monensin, two agents which neutralize intracellular acidic compartments, block the segregation of iron from transferrin after endocytosis, while neither of these reagents affects internalization of diferric transferrin into the cell. In conclusion the molecular separation of iron from transferrin inside the cell requires a non‐lysosomal acidic compartmentKeywords
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