Personalized tissue-engineered veins – long term safety, functionality and cellular transcriptome analysis in large animals
Open Access
- 13 April 2023
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Biomaterials Science
- Vol. 11 (11) , 3860-3877
Abstract
Donor veins were decellularized and reconditioned with the recipient's blood to produce autologous personalized tissue engineered veins. After 1 year in vivo, all grafts were patent and morphologically and genetically very similar with native veins.Keywords
Funding Information
- VINNOVA (2017-02130, 2017-02983)
- Västra Götalandsregionen
This publication has 50 references indexed in Scilit:
- Primer3—new capabilities and interfacesNucleic Acids Research, 2012
- Primer-BLAST: A tool to design target-specific primers for polymerase chain reactionBMC Bioinformatics, 2012
- Decellularized tissue-engineered blood vessel as an arterial conduitProceedings of the National Academy of Sciences, 2011
- An overview of tissue and whole organ decellularization processesBiomaterials, 2011
- The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR ExperimentsClinical Chemistry, 2009
- Development of Decellularized Human Umbilical Arteries as Small-Diameter Vascular GraftsTissue Engineering Part A, 2009
- Challenges in tissue engineeringJournal of The Royal Society Interface, 2006
- Small-Diameter Artificial Arteries Engineered In VitroCirculation Research, 2006
- Venous bypass and valve reconstruction: long-term efficacyVascular Medicine, 1998
- Oxygen diffusion and the distribution of cellular radiosensitivity in tumoursBritish Journal of Radiology, 1972