The Relationship Between Glaucoma and Pseudoexfoliation

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Abstract
PSEUDOEXFOLIATION (PXF), also known as the exfoliation syndrome, is the most common identifiable precursor of open-angle glaucoma worldwide.1 An extensive body of literature has documented marked geographic variations in the population distribution of PXF,2-6 despite some studies that used the same examiner.7 These different rates may reflect true racial or ethnic differences, but they could also result from use of different clinical or diagnostic criteria, ability of the examiner to detect early cases, or the examination technique.8 Most of the literature devoted to PXF has examined its well-known association with glaucoma, sometimes referred to as "capsular glaucoma" or "glaucoma capsulare."9

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