CD44 -- A New Prognostic Marker for Neuroblastoma

Authors:
  • MFM.C. Favrot
    M.C. Favrot
  • VCV. Combaret
    V. Combaret
  • CLC. Lasset
    C. Lasset

Abstract
CD44 is a cell-surface glycoprotein involved in cell-cell and cell-matrix interactions1. CD44 isoforms are expressed during progression and metastasis in colon and breast cancer and in non-Hodgkin's lymphoma2-4. We investigated the prognostic importance of the expression of CD44 in neuroblastoma, one of the most common cancers in children.