Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder
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Open Access
- 20 May 2022
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Network Open
- Vol. 5 (5) , e2213014
Abstract
Alcohol-associated liver disease (ALD) is among the most common and devastating complications of excessive alcohol use.1 Alcohol-associated liver disease represents a wide spectrum, ranging from the relatively benign hepatic steatosis to cirrhosis and hepatocellular carcinoma.2 The most aggressive form of ALD is severe alcohol-associated hepatitis, which has a 30% 3-month mortality rate.3,4 A surge in the incidence of ALD is expected with the COVID-19–related increase in alcohol use.5-7 It is, therefore, critical to prevent the development of ALD to limit the morbidity and mortality associated with excessive alcohol use.Keywords
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