Iprindole and Imipramine in Non-Psychotic Depressed Out-Patients
Authors:
- Karl RickelsKRKarl Rickels
- Hack R. ChungHCHack R. Chung
- Irma CsanalosiICIrma Csanalosi
- Lester SabloskyLSLester Sablosky
- Joseph H. SimonJSJoseph H. Simon
- 1 September 1973
- journal article
- clinical trial
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 123 (574) , 329-339
Abstract
In an earlier study this research group reported iprindole, a relatively new tricyclic derivative, to be an effective drug for use in depressed neurotic out-patients (ii). We found it to produce significantly greater improvement than placebo on a variety of outcome measures. Good response to iprindole as compared to placebo has also been reported by Hicks (5) and Daneman (3). Sterlin et al., comparing iprindole with amitriptyline in a relatively small patient sample, reported that iprindole, while faster acting, produced less overall improvement (15); differences in improvement did not, however, reach statistical significance.Keywords
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