Dual silencing of integrin αvβ3 receptor and insulin-like growth factor 1 receptor using mPEG-PCL/DDAB hybrid nanoparticle loaded siRNA in breast cancer therapy: An in vitro study on MCF-7 cells
Authors:
- 31 December 2024
- journal article
- Published by Elsevier in International Journal of Biological Macromolecules
- Vol. 294, 139334
Abstract
No abstract availableKeywords
Funding Information
- Iran National Science Foundation (4005002, QUMS.REC.402000145)
This publication has 27 references indexed in Scilit:
- HULC targets the IGF1R–PI3K-AKT axis in trans to promote breast cancer metastasis and cisplatin resistanceCancer Letters, 2022
- siRNA-based nanocarriers for targeted drug delivery to control breast cancerAdvances in Cancer Biology - Metastasis, 2022
- Co-delivery of siRNA and lycopene encapsulated hybrid lipid nanoparticles for dual silencing of insulin-like growth factor 1 receptor in MCF-7 breast cancer cell lineInternational Journal of Biological Macromolecules, 2022
- Synthesis of methoxy poly(ethylene glycol)-poly(ε-caprolactone) diblock copolymers hybridized with DDAB cationic lipid as the efficient nanocarriers for in vitro delivery of lycopene into MCF-7 breast cancer cellsJournal of Drug Delivery Science and Technology, 2021
- Novel lipid-polymer hybrid nanoparticles for siRNA delivery and IGF-1R gene silencing in breast cancer cellsJournal of Drug Delivery Science and Technology, 2018
- Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1RFood and Chemical Toxicology, 2018
- Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1Cytokine & Growth Factor Reviews, 2017
- Fabrication and functional attributes of lipidic nanoconstructs of lycopene: An innovative endeavour for enhanced cytotoxicity in MCF-7 breast cancer cellsColloids and Surfaces B: Biointerfaces, 2017
- PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectivesEuropean Journal of Medicinal Chemistry, 2016
- siRNA Design Principles and Off-Target Effects2013