Formation of the COOH‐terminal amide group of thyrotropin‐releasing‐factor
Authors:
- Intisar HusainIHIntisar Husain
- Suresh S. TateSTSuresh S. Tate
- 21 February 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 152 (2) , 277-281
Abstract
The precursors of peptide hormones that possess a COOH‐terminal α‐amide group contain a glycine residue following the amino acid which is amidated in the hormone. 〈Glu—His—Pro—Gly was synthesized as a putative precursor of thyroliberin. Bovine pituitary neurosecretory granules were shown to contain an amide group‐forming activity associated with an M r of about 62000 protein(s) which converts the tetrapeptide to thyroliberin.This publication has 14 references indexed in Scilit:
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