DNA Gene's Basic Structure as a Nonperturbative Circuit Quantum Electrodynamics: Is RNA Polymerase II the Quantum Bus of Transcription?
Authors:
- Annie Riera LealALAnnie Riera Leal
- Raul Riera ArocheRARaul Riera Aroche
- Yveth Marlene Ortiz GarciaYGYveth Marlene Ortiz Garcia
- Esli Camila Sanchez MorenoEMEsli Camila Sanchez Moreno
- Jose Saulo Enriquez CervantesJCJose Saulo Enriquez Cervantes
- Andrea Carolina Machado SulbaranAndrea Carolina Machado Sulbaran
Preprint
- 25 September 2024
- preprint
- Published by MDPI AG in Preprints.org
Abstract
Previously, we described that Adenine, Thymine, Cytosine, and Guanine nucleobases were superconductors in a quantum superposition of phases on each side of the central Hydrogen bond acting as a Josephson Junction. Genomic DNA has two strands wrapped helically around one another, but during transcription, they are separated by the RNA polymerase II to form a molecular condensate called the transcription bubble. Successive steps involve the bubble translocation along the gene body. This work discusses how quantum information transfer and entanglement can be achieved by modeling DNA as a combination ofKeywords
All Related Versions
This publication has 71 references indexed in Scilit:
- Toward Molecular Spin Qubit Devices: Integration of Magnetic Molecules into Solid-State DevicesACS Applied Electronic Materials, 2023
- The effects of RNA.DNA-DNA triple helices on nucleosome structures and dynamicsBiophysical Journal, 2023
- Biomolecular Condensates in the NucleusTrends in Biochemical Sciences, 2020
- Standard Gibbs energy of metabolic reactions: II. Glucose-6-phosphatase reaction and ATP hydrolysisBiophysical Chemistry, 2017
- KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase IIMolecular Cell, 2016
- TFIIH Phosphorylation of the Pol II CTD Stimulates Mediator Dissociation from the Preinitiation Complex and Promoter EscapeMolecular Cell, 2014
- Structural basis of transcription elongationBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2013
- Conservation between the RNA Polymerase I, II, and III Transcription Initiation MachineriesMolecular Cell, 2012
- How Does the cAMP-Dependent Protein Kinase Catalyze the Phosphorylation Reaction: An ab Initio QM/MM StudyJournal of the American Chemical Society, 2005
- ATP synthase: what we know about ATP hydrolysis and what we do not know about ATP synthesisBiochimica et Biophysica Acta (BBA) - Bioenergetics, 2000