Allele-selective and pan-allelic huntingtin lowering differentially affect neuronal homeostasis and BDNF transport
Authors:
- Romane A. LahayeRLRomane A. Lahaye
- Aude LemesleALAude Lemesle
- Laurent CotterLCLaurent Cotter
- Donya El AkroutiDADonya El Akrouti
- Virginie RedekerVRVirginie Redeker
- Mathilde LouçãMLMathilde Louçã
- Hélène Jean-JacquesHJHélène Jean-Jacques
- Yuanjing LiuYLYuanjing Liu
- Abbie MaguireAMAbbie Maguire
- Naoki IwamotoNINaoki Iwamoto
- Michael ByrneMBMichael Byrne
- Chandra VargeeseCVChandra Vargeese
Open Access
- 27 October 2026
- journal article
- Published by Elsevier in Molecular Therapy Nucleic Acids
- Vol. 37 (4)
Abstract
No abstract availableFunding Information
- Agence Nationale de la Recherche
- Fondation pour la Recherche Médicale
This publication has 71 references indexed in Scilit:
- Huntington’s Disease: Latest Frontiers in TherapeuticsCurrent Neurology and Neuroscience Reports, 2024
- Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions2022
- Directly Reprogrammed Huntington's Disease Neural Precursor Cells Generate Striatal Neurons Exhibiting Aggregates and Impaired Neuronal MaturationStem Cells, 2021
- Gene Set Knowledge Discovery with EnrichrCurrent Protocols, 2021
- Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s DiseaseCell Reports, 2018
- A randomized, double‐blind, placebo‐controlled trial evaluating cysteamine in Huntington's diseaseMovement Disorders, 2017
- Vesicular Glycolysis Provides On-Board Energy for Fast Axonal TransportCell, 2013
- Role of mitochondrial dysfunction in the pathogenesis of Huntington's diseaseBrain Research Bulletin, 2009
- Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along MicrotubulesCell, 2004
- A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomesCell, 1993