Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?
- 10 January 2023
- journal article
- review article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 117 (3) , 455-466
Abstract
No abstract availableKeywords
Funding Information
- Health Services Research and Development
- U.S. Department of Veterans Affairs (BXI01BX004511)
This publication has 168 references indexed in Scilit:
- Alterations in metabolic pathways and networks in Alzheimer’s diseaseTranslational Psychiatry, 2013
- Neural Mechanisms of ForagingScience, 2012
- Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and womenEuropean Journal of Clinical Nutrition, 2011
- Neuronal basis of sequential foraging decisions in a patchy environmentNature Neuroscience, 2011
- Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 DiabetesArchives of Neurology, 2011
- A high fructose diet impairs spatial memory in male ratsNeurobiology of Learning and Memory, 2009
- The Role of Metabolic Disorders in Alzheimer Disease and Vascular DementiaArchives of Neurology, 2009
- Reactions of Peroxynitrite with Uric Acid: Formation of Reactive Intermediates, Alkylated Products and Triuret, and In Vivo Production of Triuret Under Conditions of Oxidative StressNucleosides, Nucleotides & Nucleic Acids, 2009
- Differential effects of central fructose and glucose on hypothalamic malonyl–CoA and food intakeProceedings of the National Academy of Sciences, 2008
- Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feedingAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2008