A fatal case of primary cutaneous gamma–delta T‐cell lymphoma complicated by HLH and cardiac amyloidosis
Open Access
- 17 November 2014
- journal article
- Published by Wiley in Clinical Case Reports
- Vol. 3 (1) , 34-38
Abstract
Key Clinical Message: Gamma–delta T‐cell lymphomas (GD‐TCL) are rare and rapidly fatal neoplasms that are often associated with Hemophagocytic Lymphohistiocytosis (HLH), a syndrome of fevers, cytopenias, and multiorgan failure that often leads to a rapid death. We report the first case demonstrating an association between GD‐TCL, HLH, and cardiac amyloidosis, presenting a novel mechanism for rapid deterioration in these patients.Keywords
This publication has 23 references indexed in Scilit:
- Functions of skin-resident γδ T cellsCellular and Molecular Life Sciences, 2011
- Serum Neopterin Levels as a Diagnostic Marker of Hemophagocytic Lymphohistiocytosis SyndromeClinical and Vaccine Immunology, 2011
- Clinical characteristics of T-cell lymphoma associated with hemophagocytic syndrome: Comparison of T-cell lymphoma with and without hemophagocytic syndromeLeukemia & Lymphoma, 2008
- Antigen recognition by γδ T cellsImmunological Reviews, 2007
- WHO-EORTC classification for cutaneous lymphomasBlood, 2005
- A Case Report of the Effect of Plasma Exchange on Reactive Hemophagocytic Syndrome Associated with Toxic Shock SyndromeTherapeutic Apheresis and Dialysis, 2004
- Hepatosplenic T-cell lymphoma is a rare clinicopathologic entity with poor outcome: report on a series of 21 patientsBlood, 2003
- Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphomaBlood, 2003
- Plasmapheresis for the treatment of acute pancreatitis induced by hemophagocytic syndrome related to hypertriglyceridemiaJournal of Clinical Apheresis, 2003
- TCRgammadelta Cells: A Specialized T-Cell Subset in the Immune SystemAnnual Review of Cell and Developmental Biology, 1995