Developing treatment for spinal and bulbar muscular atrophy
- 31 December 2012
- journal article
- review article
- Published by Elsevier in Progress in Neurobiology
- Vol. 99 (3) , 257-261
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Overexpression of IGF-1 in Muscle Attenuates Disease in a Mouse Model of Spinal and Bulbar Muscular AtrophyNeuron, 2009
- Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophyHuman Molecular Genetics, 2009
- Polyglutamine-Expanded Androgen Receptor Truncation Fragments Activate a Bax-Dependent Apoptotic Cascade Mediated by DP5/HrkJournal of Neuroscience, 2009
- Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophyAnnals of Neurology, 2009
- Mitochondrial abnormalities in spinal and bulbar muscular atrophyHuman Molecular Genetics, 2008
- HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPSNature, 2007
- Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicityHuman Molecular Genetics, 2007
- ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptorNature Medicine, 2007
- 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degenerationNature Medicine, 2005
- Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophyNature, 1991