Inflammatory Bowel Disease Management During the COVID-19 Outbreak: The Ten Do’s and Don’ts from the ECCO-COVID Taskforce
Authors:
- 29 July 2020
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Crohn's and Colitis
- Vol. 14 (Supplement) , S798-S806
Abstract
Our knowledge of COVID-19 is changing and evolving rapidly, with novel insights and recommendations, almost on a daily basis. It behooves the medical community to provide updated information on a regular basis, on best practice to facilitate optimal care of infected patients and on appropriate advice for the general population. This is particularly important in the case of patients with chronic conditions, such as inflammatory bowel disease [IBD]. In this review, we have compiled existing evidence on the impact of COVID-19 in IBD patients and provide guidance on the most appropriate care to adopt during the pandemic. Our review highlights that IBD, per se, is not a risk factor for COVID-19. However, all IBD patients with symptoms should be tested for SARS-CoV-2 and the procedures for disease management should be carefully adapted: [i] in SARS-CoV-2-positive IBD patients, medical treatments should be re-evaluated [with a particular focus on corticosteroids] always with the purpose of treating active disease and maintaining remission; [ii] non-urgent surgeries and endoscopic procedures should be postponed for all patients; [iii] online consultancy should be implemented; and [iv] hospitalization and surgery should be limited to life-threatening situations.Keywords
Funding Information
- ECCO
- IOIBD
This publication has 67 references indexed in Scilit:
- Inflammatory Bowel Disease Patients Are at Increased Risk of Invasive Pneumococcal Disease: A Nationwide Danish Cohort Study 1977–2013American Journal of Gastroenterology, 2015
- Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirusAntiviral Research, 2015
- A Phase 2 Study of Tofacitinib, an Oral Janus Kinase Inhibitor, in Patients With Crohn’s DiseaseClinical Gastroenterology and Hepatology, 2014
- Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including AlisporivirVirus Research, 2014
- Human Coronaviruses: Insights into Environmental Resistance and Its Influence on the Development of New Antiseptic StrategiesViruses, 2012
- Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trialGut, 2011
- Effects of the ACE2 inhibitor GL1001 on acute dextran sodium sulfate-induced colitis in miceInflammation Research, 2009
- Persistent shedding of viable SARS-CoV in urine and stool of SARS patients during the convalescent phaseEuropean Journal of Clinical Microbiology & Infectious Diseases, 2005
- ACE2: from vasopeptidase to SARS virus receptorTrends in Pharmacological Sciences, 2004
- Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndromeThe Lancet, 2004