Bubble sorting in pinched microchannels for ultrasound contrast agent enrichment
- 24 July 2015
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 15 (18) , 3716-3722
Abstract
We present a lab-on-a-chip methodology for the enrichment of ultrasound contrast agents using pinched flow fractionation. We extend the modelling to include relatively large particles, by combining numerical and experimental results. Due to the simple operating principle, sorting devices based on this method are ideally suited for paralellization.Keywords
This publication has 27 references indexed in Scilit:
- Theranostic mRNA-loaded Microbubbles in the Lymphatics of Dogs: Implications for Drug DeliveryTheranostics, 2015
- Ultrasound-Targeted Microbubble Destruction to Deliver siRNA Cancer TherapyCancer Research, 2012
- Dynamics of Coated Microbubbles Adherent to a WallUltrasound in Medicine & Biology, 2011
- Targeted renal therapies through microbubbles and ultrasound☆Advanced Drug Delivery Reviews, 2010
- Microbubbles in ultrasound-triggered drug and gene deliveryAdvanced Drug Delivery Reviews, 2008
- On-chip generation of microbubbles as a practical technology for manufacturing contrast agents for ultrasonic imagingLab on a Chip, 2007
- Microbubble Contrast AgentsInvestigative Radiology, 2006
- The use of microbubbles to target drug deliveryCardiovascular Ultrasound, 2004
- Microbubbles in medical imaging: current applications and future directionsNature Reviews Drug Discovery, 2004
- Higher harmonics of vibrating gas-filled microspheres. Part one: simulationsUltrasonics, 1994