Phytochemical Profiling and Biological Activity of the Australian Carnivorous Plant, Drosera magna

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Abstract
Phytochemical profiling was undertaken on the crude extracts of Drosera magna to determine the nature of the chemical constituents present. In total, three new flavonol diglycosides (1–3), one new flavan-3-ol glycoside (4), and 12 previously reported compounds of the flavonol (5, 9), flavan-3-ol (15), flavanone (8), 1,4-napthoquinone (6, 7, 13, 14), 2,3-dehydroxynapthalene-1,4-dione (10–12), and phenolic acid (16) structure classes were isolated and identified. Compounds 1–9, 13, 17, and 18 were assessed for antimicrobial activity, with compounds 6, 7, 8, and 9 showing significant activity. Compounds 1, 2, and 6 were also evaluated for anthelmintic activity against larval forms of Hemonchus contortus, with compound 6 being active.
Funding Information
  • Australian Research Council (LE170100065, LP160100058)
  • Wellcome Trust
  • RMIT University
  • University of Queensland

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