A POTENT NEW β2‐ADRENOCEPTOR BLOCKING AGENT
Authors:
Open Access
- 19 July 1977
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 60 (3) , 357-362
Abstract
1 (t‐Butyl‐amino‐3‐ol‐2‐propyl) oximino‐9 fluorene is a new β2‐adrenoceptor blocking agent with a pA2 of 9.23 ± 0.25 on isolated trachea.2 It provokes hypertension in normotensive rats and does not prevent arterial hypertension in SHR rats, although it does prevent the renin secretion normally induced by isoprenaline infusion.Keywords
This publication has 7 references indexed in Scilit:
- Dopamine-induced neurogenic vasodilatation in isolated perfused muscle preparation of the dogNaunyn-Schmiedeberg's Archives of Pharmacology, 1975
- Effects of Prolonged Treatment with Adrenergic β‐receptor Antagonists on Blood Pressure, Cardiovascular Design and Reactivity in Spontaneously Hypertensive Rats (SHR)Acta Physiologica Scandinavica, 1974
- Pressor Effect of Beta Blocking Agents in RatsCanadian Journal of Physiology and Pharmacology, 1972
- The actions of selective β-receptor antagonists on the guinea pig tracheaEuropean Journal of Pharmacology, 1970
- A critical evaluation of three methods for the study of adrenergic beta-blocking and anti-arrhythmic agentsEuropean Journal of Pharmacology, 1969
- SYNTHETIC SUBSTITUTES FOR QUINIDINEBritish Journal of Pharmacology and Chemotherapy, 1946
- Versuchsanordnung zu Untersuchungen an der BronchiàlmuskulaturNaunyn-Schmiedeberg's Archives of Pharmacology, 1940