Dental condition and salivary characteristics in Vietnamese patients with chronic kidney disease

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Abstract
Objectives: To determine the dental status and salivary characteristics and to analyse the correlation between creatinine clearance with DMFT index and salivary flow rate in Vietnamese patients with chronic kidney disease (CKD).Methods: This study was conducted on 111 CKD and 109 non‐CKD patients. The socio‐demographic characteristics associated with dental habits and xerostomia status were recorded from a self‐administered questionnaire. Dental status (DT, MT, FT) and salivary characteristics (flow rate; pH; buffering capacity; urea and creatinine concentrations) were examined. The multivariate regression models were used to assess the correlation of creatinine clearance with DMFT index and salivary flow rate with adjustment for confounders.Results: Patients with CKD made MT and DMFT indices significantly higher than non‐CKD subjects. Chronic kidney disease patients had reduced salivary flow rate; but higher xerostomia level, salivary pH and buffering capacity than those in non‐CKD subjects. Results of multivariate regression models showed that with lower creatinine clearance 1 mL/min, DMF index was higher 0.02 teeth, and salivary flow rate lower 0.003 mL/min.Conclusions: There were no differences in dental status between patients with CKD and those without CKD, except that poor renal function is directly related with a higher DMFT index and lower salivary flow rate. Dental professionals should pay greater attention to oral problems during the progression of CKD to prevent deterioration of oral health.

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