The potential of PCNA inhibition as a therapeutic strategy in cervical cancer
Open Access
- 27 November 2023
- journal article
- review article
- Published by Wiley in Journal of Medical Virology
- Vol. 95 (11) , e29244
Abstract
Cervical cancers are the fourth most common and most deadly cancer in women worldwide. Despite being a tremendous public health burden, few novel approaches to improve care for these malignancies have been introduced. We discuss the potential for proliferating cell nuclear antigen (PCNA) inhibition to address this need as well as the advantages and disadvantages for compounds that can therapeutically inhibit PCNA with a specific focus on cervical cancer.Keywords
Funding Information
- National Institutes of Health (P20GM130448, P20GM103418)
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