Heterogeneous Reductive Isomerization Reaction Using Catalytic Pd/C and H2
Authors:
- 14 May 2005
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 7 (12) , 2513-2516
Abstract
A highly selective catalytic reductive isomerization reaction is described. The extremely mild and neutral reaction conditions (10% Pd/C, H2, and MeOH at 0 °C) tolerate a wide range of functional groups and generally result in excellent yields. Mechanistic studies suggest that this reaction does not proceed via a stepwise reduction/elimination sequence or a π-allylpalladium intermediate.Keywords
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