Vitamin B6Levels in Rat Tissues

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Abstract
The level of total vitamin B6 in the livers of deficient and control rats with and without the administration of the antivitamin, deoxypyridoxin, has been described in previous reports from this laboratory (Beaton, Smith & McHenry, 1953 ; Sheppard & McHenry, 1946). The level of the vitamin in other tissues of normal rats has already been reported by others (Williams, Eakin & McMahan, 1941). Stoerk (1949-50) has suggested that the administration of deoxypyridoxin prevents reduction in the vitamin B, of the livers of deprived animals; details of his experimental procedures were not given. In this paper, observations are reported on the administration of deoxypyridoxin to control and vitamin B,-deprived rats, on the relation of the vitamin B, levels in three organs to the absence or presence of dietary pyridoxin, on time studies of the developing vitamin B6 deficiency in the rat, and on the comparison of bodyweight increases with the level of vitamin B, in the liver. EXPERIMENTAL AND RESULTS Methods Wistar strain albino rats were employed and were housed in individual, screen

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