Providing Standardized Gene Nomenclature for Domestic Ungulate Scavenger Receptor Genes
Authors:
Open Access
- 24 June 2025
- journal article
- Vol. 2025
Abstract
Scavenger Receptor (SCAR) genes are a heterogeneous group involved in innate immunity and immunomodulation. While standardized gene nomenclature is provided for model organism SCAR genes, ungulates have novel SCAR genes which have not been systematically classified. This study compares SCAR genes for five representative ungulate species which are selected based on their agricultural importance and representation. We identify and classify twenty-seven SCAR genes common to all species and provide standardized gene nomenclature for genes novel to these ungulate species. Notably, we provide standardized gene nomenclature for the previously studied Workshop Cluster 1 (WC1) genes which are absent in model organisms.Keywords
This publication has 17 references indexed in Scilit:
- Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T CellsImmunity, 2013
- Scavenger receptor WC1 contributes to the γδ T cell response to LeptospiraMolecular Immunology, 2011
- Evolution of the CD163 family and its relationship to the bovine gamma delta T cell co-receptor WC1BMC Ecology and Evolution, 2010
- Antigen recognition by γδ T cellsImmunological Reviews, 2007
- Differential mRNA expression in circulating γδ T lymphocyte subsets defines unique tissue-specific functionsJournal of Leukocyte Biology, 2003
- Natural and synthetic non-peptide antigens recognized by human γδ T cellsNature, 1995
- Prominence of γδ T cells in the ruminant immune systemImmunology Today, 1991
- Differentiation antigens expressed predominantly on CD4− CD8− T lymphocytes (WC1, WC2)Veterinary Immunology and Immunopathology, 1991
- A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytesNature, 1986
- Identification of a putative second T-cell receptorNature, 1986