Structural Insight into the Differential Effects of Omega-3 and Omega-6 Fatty Acids on the Production of Aβ Peptides and Amyloid Plaques
Authors:
- Zareen AmtulZAZareen Amtul
- Markus UhrigMUMarkus Uhrig
- Richard F. RozmahelRRRichard F. Rozmahel
- Konrad BeyreutherKBKonrad Beyreuther
Open Access
- 1 February 2011
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 286 (8) , 6100-6107
Abstract
No abstract availableKeywords
This publication has 50 references indexed in Scilit:
- Oleic Acid Ameliorates Amyloidosis in Cellular and Mouse Models of Alzheimer's DiseaseBrain Pathology, 2010
- Palmitic acid-treated astrocytes induce BACE1 upregulation and accumulation of C-terminal fragment of APP in primary cortical neuronsNeuroscience Letters, 2006
- Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic miceNeurobiology of Disease, 2006
- Docosahexaenoic acid-induced amelioration on impairment of memory learning in amyloid β-infused rats relates to the decreases of amyloid β and cholesterol levels in detergent-insoluble membrane fractionsBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005
- Pathways towards and away from Alzheimer's diseaseNature, 2004
- Piecing Together Alzheimer'sScientific American, 2000
- Alzheimer's Disease βA4 Protein Release and Amyloid Precursor Protein Sorting Are Regulated by Alternative SplicingJournal of Biological Chemistry, 1996
- Intracellular Generation of Amyloid β-Protein from Amyloid β-Protein Precursor Fragment by Direct Cleavage with β- and γ-SecretaseBiochemical and Biophysical Research Communications, 1996
- Amyloid β/A4 Precursor Protein (APP) Processing in LysosomesaAnnals of the New York Academy of Sciences, 1992
- n–3 and n–6 polyunsaturated fatty acids have different effects on acyl-CoA:cholesterol acyltransferase in J774 macrophagesBiochemistry and Cell Biology, 1992