Relay Catalysis by a Metal-Complex/Brønsted Acid Binary System in a Tandem Isomerization/Carbon−Carbon Bond Forming Sequence
Authors:
- 14 October 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 130 (44) , 14452-14453
Abstract
A one-pot tandem isomerization/carbon−carbon bond forming sequence catalyzed by a ruthenium complex/Brønsted acid binary system is demonstrated. The method enables the use of readily available allylamides to deliver reactive imines under relay catalysis using a binary catalytic system. Subsequent Brønsted acid catalyzed carbon−carbon bond forming reactions of the generated imines with nucleophilic components afforded Friedel−Crafts and Mannich products in good yields.Keywords
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