Dating the Heart: Exploring Cardiomyocyte Renewal in Humans
Authors:
- 1 January 2017
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 32 (1) , 33-41
Abstract
Regenerative mechanisms reported in the hearts of lower vertebrates have been recapitulated in the mammalian milieu, and recent studies have provided strong evidence for cardiomyocyte turnover in humans. These findings speak to an emerging consensus that adult mammalian cardiomyocytes do have the ability to divide, and it stands to reason that enrichment of this innate proliferative capacity should prove essential for complete cardiac regeneration.Keywords
Funding Information
- Ragnar Söderberg Foundation
- Vetenskapsrådet (Swedish Research Council)
- Jeanssons Foundations
- Åke Wibergs Foundation
- Karolinska Institutet (KI)
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