Abstract
This work describes the synthesis of bis(indolyl)methanes by using effective combination of ultrasound and deep eutectic solvent. This methodology offers momentous improvements over various options for the synthesis of bis(indolyl)methanes with regard to yield of products, simplicity in operation, and green aspects by avoiding toxic catalysts and solvents. Further, the deep eutectic solvent can be reused and recovered for several times without loss of activity.

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