Hibernoma

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Abstract
A 65-year-old man with several subcutaneous masses (clinically diagnosed as lipomata), underwent Tc-99m tetrofosmin scanning for chest pain. One of these masses (in the right thigh) was incidentally noted to take up tetrofosmin. Computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated a fat-containing lesion, and F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET or C-PET) showed active uptake. Biopsy showed the lesion to be a hibemoma. Hibemoma is a benign but metabolically active tumor of brown fat origin. Brown fat is a major heat producer in the newborn and contains high levels of mitochondria. This high metabolic rate probably explains the uptake of Tc-99m tetrofosmin and F-18 FDG. Nevertheless, without a biopsy, the imaging studies could not exclude liposarcoma.Barry E. Chatterton, Dominic Mensforth, Brendon J. Coventry and Penelope Cohenhttp://cat.inist.fr/?aModele=afficheN&cpsidt=13638310http://journals.lww.com/nuclearmed/Citation/2002/05000/Hibernoma__Intense_Uptake_Seen_on_Tc_99m.16.asp

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