Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

This publication has 51 references indexed in Scilit:

• The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism
  Cell, 2016
• Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice
  Journal of Neuroscience, 2015
• Agonist-induced internalisation of the glucagon-like peptide-1 receptor is mediated by the Gαq pathway
  Biochemical Pharmacology, 2015
• Differential Activation and Modulation of the Glucagon-Like Peptide-1 Receptor by Small Molecule Ligands
  Molecular Pharmacology, 2013
• Emergent biological properties of arrestin pathway-selective biased agonism
  Journal of Receptors and Signal Transduction, 2013
• Therapeutic potential of β-arrestin- and G protein-biased agonists
  Trends in Molecular Medicine, 2011
• Allosteric Ligands of the Glucagon-Like Peptide 1 Receptor (GLP-1R) Differentially Modulate Endogenous and Exogenous Peptide Responses in a Pathway-Selective Manner: Implications for Drug Screening
  Molecular Pharmacology, 2010
• GLP-1 Mediates Antiapoptotic Effect by Phosphorylating Bad through a β-Arrestin 1-mediated ERK1/2 Activation in Pancreatic β-Cells
  Journal of Biological Chemistry, 2010
• β-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic β cells
  Proceedings of the National Academy of Sciences, 2008
• Functional expression of the rat glucagon-like peptide-I receptor, evidence for coupling to both adenylyl cyclase and phospholipase-C.
  Endocrinology, 1993