Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo
Open Access
- 16 October 2014
- journal article
- Published by American Society of Hematology in Blood
- Vol. 124 (16) , 2523-2532
Abstract
Key Points: Single cell lineage tracing shows early separation of blood-endothelial precursors in the mouse embryo. Hemogenic endothelium in the YS generates the blood-endothelial common lineage and produces definitive precursors.Keywords
This publication has 42 references indexed in Scilit:
- Erythroid/Myeloid Progenitors and Hematopoietic Stem Cells Originate from Distinct Populations of Endothelial CellsCell Stem Cell, 2011
- Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM regionJournal of Experimental Medicine, 2011
- Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryoBlood, 2011
- The haemangioblast generates haematopoietic cells through a haemogenic endothelium stageNature, 2009
- Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem CellsCell Stem Cell, 2008
- Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesisBlood, 2008
- Transgenic mice with hematopoietic and lymphoid specific expression of CreEuropean Journal of Immunology, 2003
- Temporal Cre‐mediated recombination exclusively in endothelial cells using Tie2 regulatory elementsGenesis, 2002
- Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in VivoDevelopmental Biology, 2001
- Cell cycle analysis in the mouse egg-cylinderExperimental Cell Research, 1971