Use of Deep Learning to Analyze Social Media Discussions About the Human Papillomavirus Vaccine

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Abstract
Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States.1 HPV infections cause approximately 33 700 cases of cancer every year in the United States, including cervical, vaginal, vulvar, penile, and anal cancers.2,3 The HPV vaccine has been available since 2006 to protect against HPV-associated cancers and is recommended for adolescents starting at age 9 years through age 26 years if not vaccinated, and, for some people, up to age 45 years.4 Unfortunately, compared with other adolescent vaccines (eg, tetanus, diphtheria, pertussis [Tdap] and meningococcal B [MenB]), HPV vaccine rates remain low, with approximately 51% of adolescents not completing the HPV vaccination series.5 The most common reasons for parental declination of HPV vaccine include safety concerns, perceived lack of necessity, and lack of knowledge about the vaccine and HPV.6 For this reason, knowledge about the prevalence of these concerns can inform tailored strategies to mitigate them and improve immunization rates.

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